‘The 2nd is nanopores, which happens to be our oldest line of investigate and that has now led to DNA sequencers depending on nanopores. We pull personal DNA strands by way of a nanopore and may then study off the nucleotide sequence. Very lately, we even managed to read out a single protein for The 1st time working with This method. But this line of investigation is not merely about building tools, but additionally about real Organic inquiries.
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Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
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The coiled-coil from the human Rad50 DNA repair protein has certain segments of increased adaptability
Duration control of unique https://www.ceesdekker.net carbon nanotubes by nanostructuring With all the scanning tunneling microscope
2000, discovery that nanotubes can carry remarkable substantial recent densities; fixed the controversial difficulty of electronic transport by DNA molecules by measurements of insulating conduct at the single molecule stage; and demonstration of the AFM technique for solitary-molecule manipulation of nanotubes
‘You should not just think of the queries of tomorrow, but in addition look at the issues on the working day right after tomorrow’
Really neat, but that wasn’t truly wherever my interest lay. I desired to pioneer And that i had the feeling which was now not possible, since the most appealing fundamental insights experienced now been uncovered. But my area experienced created several remarkable new resources to measure particular person molecules. I made a decision that I desired to use this to biology, to take a look at it from the Actual physical standpoint.’
Screening pseudotopological and nontopological products for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments
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2013, managed shaping of Dwell bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations within the handedness of histone tetrasomes